TTF-1 / Thyroid-Specific TF 抗体
适用: 人, 小鼠, 大鼠
FACS, IHC, IHC (p), IF
宿主: 小鼠
Monoclonal
8G7G3-1
unconjugated
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- 抗原
- TTF-1 / Thyroid-Specific TF
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- Rat TTF-1 / Thyroid-Specific TF
- 纯化方法
- Protein G purified
- 免疫原
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Rat full length TTF1 / NKX2.1 recombinant protein.
Type of Immunogen: Recombinant protein - 克隆位点
- 8G7G3-1
- 亚型
- IgG1 kappa
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- 应用备注
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Approved: Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL)
Usage: This mAb recognizes a protein of 40 kDa, identified as Thyroid transcription factor 1. TTF1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. antibody to TTF1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. The antibody can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF1 reactivity is also seen in thyroid malignancies. ELISA: Order BSA-free format for coating. - 说明
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Target Species of Antibody: Rat
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2°C to 8°C.
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- 抗原
- TTF-1 / Thyroid-Specific TF
- 背景
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Name/Gene ID: NKX2-1
Synonyms: NKX2-1, BCH, Benign chorea, Homeobox protein Nkx-2.1, NK-2, NKX2.1, NK-2 homolog A, Thyroid transcription factor 1, NK2 homeobox 1, TTF-1, BHC, Thyroid nuclear factor 1, TITF1, NKX2A, TEBP - 基因ID
- 7080
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