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TIMP3 抗体 (AA 198-211)

The 兔 多克隆 anti-TIMP3 antibody is suitable to detect TIMP3 in samples from 人, 大鼠, Cow, 犬, 绵羊, Pig, 猴, Chimpanzee 和 Gibbon. It has been validated for WB 和 ELISA.
产品编号 ABIN2744876
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TIMP3 抗体 (AA 198-211) (ABIN2744876)

抗原

See all TIMP3 抗体
TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

适用

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人, 大鼠, Cow, 犬, 绵羊, Pig, 猴, Chimpanzee, Gibbon

宿主

  • 99
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克隆类型

  • 101
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多克隆

标记

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This TIMP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 198-211

    特异性

    Human TIMP3

    纯化方法

    Immunoaffinity purified

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP3(198-211aa WAPPDKSIINATDP). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Ferret, Sheep, Cat, Bovine, Pig, Dog (100%), Mouse, Bat, Hamster, Opossum, Zebra finch, Chicken, Lizard (93%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: ELISA (0.1 - 0.5 μg/mL), WB (0.5 - 1 μg/mL)

    Usage: The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD).

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Sterile distilled water

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
  • 抗原

    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

    别名

    TIMP3

    背景

    Name/Gene ID: TIMP3

    Synonyms: TIMP3, HSMRK222, K222TA2, MIG-5 protein, K222, SFD, Metalloproteinase inhibitor 3, Protein MIG-5, TIMP-3

    基因ID

    7078
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