SUMO2 抗体
Quick Overview for SUMO2 抗体 (ABIN2744596)
抗原
See all SUMO2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human SUMO2 + SUMO3.
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纯化方法
- Protein G purified
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免疫原
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Recombinant human SUMO2 protein.
Type of Immunogen: Recombinant protein -
亚型
- IgG1 kappa
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anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibody
SUMO2 适用: 人, 大鼠 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SUMO2-1199 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 63-93) antibodySUMO2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-95) antibodySUMO2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibodySUMO2 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SM23-496 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-95) antibodySUMO2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibodySUMO2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) antibodySUMO2 适用: 人, 大鼠 IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal SUMO2-1199 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 49-81) antibodySUMO2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-95) antibodySUMO2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Small Ubiquitin Related Modifier 2 (SUMO2) (AA 1-93) antibodySUMO2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal AT10F1 unconjugated
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应用备注
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Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)
Usage: This antibody reacts with both SUMO2 and SUMO3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursors that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets for a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO1/2/3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO1 utilizes Ubc9 for conjugation to several targets, which include MDM2, p53, PML and RanGap1. SUMO2/3 contribute to a greater percentage of protein modification than does SUMO1 and they can form polymeric chains. In addition, SUMO3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer's disease. ELISA: Order BSA-free format for coating. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C to 8°C.
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- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
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别名
- SUMO2 + SUMO3
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背景
- This antibody detects: SUMO2 + SUMO3
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途径
- Methionine Biosynthetic Process
抗原
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