Plasma Cell 抗体
Our Local Distributor
北京 101111
Quick Overview for Plasma Cell 抗体 (ABIN2743663)
抗原
适用
宿主
克隆类型
应用范围
克隆位点
-
-
特异性
- Human Plasma Cell Marker
-
无交叉反应
- 大鼠
-
纯化方法
- Protein G purified
-
免疫原
- Pancreatic cancer-related mucin.
-
亚型
- IgG2a
-
-
-
应用备注
-
Approved: IHC, IHC-P (0.5 - 1 μg/mL)
Usage: This antibody recognizes an intra-cytoplasmic marker antigen which shows a very high degree of specificity for plasma cells. This marker protein is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm. their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This marker antibody superbly recognizes normal and neoplastic plasma cells in routine formalin/paraffin tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this plasma cell marker antibody is not suitable for staining frozen tissues. -
说明
-
Target Species of Antibody: Human
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store at 2°C to 8°C.
-
-
- Plasma Cell
抗原
-