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PAX6 抗体

This anti-PAX6 antibody is a 小鼠 单克隆 antibody detecting PAX6 in WB, IF, FACS, IHC 和 IHC (fro). Suitable for 人, 小鼠, 大鼠 和 小鸡.
产品编号 ABIN2743487
发货至: 中国

Quick Overview for PAX6 抗体 (ABIN2743487)

抗原

See all PAX6 抗体
PAX6 (Paired Box 6 (PAX6))

适用

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人, 小鼠, 大鼠, 小鸡

宿主

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小鼠

克隆类型

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单克隆

标记

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This PAX6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

PAX6-496
  • 特异性

    Human PAX6

    纯化方法

    Protein G purified

    免疫原

    Recombinant human PAX6 protein.

    Type of Immunogen: Recombinant protein

    亚型

    IgG1 kappa
  • 应用备注

    Approved: Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)

    Usage: PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain. ELISA: Order BSA-free antibody format for coating.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2°C to 8°C.
  • 抗原

    PAX6 (Paired Box 6 (PAX6))

    别名

    PAX6

    背景

    Name/Gene ID: PAX6

    Synonyms: PAX6, AN2, D11S812E, MGDA, Oculorhombin, Paired box 6, Paired box homeotic gene-6, AN, Aniridia type II protein, WAGR, Paired box protein Pax-6

    基因ID

    5080

    途径

    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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