Keratin 6 抗体 (C-Term)
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北京 101111
Quick Overview for Keratin 6 抗体 (C-Term) (ABIN2742495)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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特异性
- Human KRT6 / CK6 / Cytokeratin 6
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纯化方法
- Protein G purified
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免疫原
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A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from the C-terminus of human Cytokeratin 6. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Horse (100%), Marmoset, Mouse, Rat, Ferret, Bat, Hamster, Elephant, Dog (91%), Sheep, Bovine (82%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG2a kappa
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anti-Keratin 6 (KRT6) antibody
KRT6 适用: 人, 小鼠, 大鼠 IF, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6 (KRT6) antibodyKRT6 适用: 人 IHC 宿主: 兔 Monoclonal 606R unconjugated Recombinant Antibody
anti-Keratin 6 (KRT6) antibodyKRT6 适用: 人 WB 宿主: 小鼠 Monoclonal 4A1 unconjugated
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应用备注
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Approved: Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL)
Usage: This antibody recognizes a protein of 56 kDa, identified as cytokeratin 6 (CK6) or Keratin 6. In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express Cytokeratin 6 and 16. Keratin 6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of Cytokeratin 6 is particularly associated with differentiation. ELISA: Order BSA-free antibody format for coating. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C to 8°C.
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- Keratin 6 (KRT6)
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别名
- KRT6 / CK6 / Cytokeratin 6
抗原
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