CD79a 抗体 (AA 202-216)
Quick Overview for CD79a 抗体 (AA 202-216) (ABIN2739648)
抗原
See all CD79a (CD79A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 202-216
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特异性
- Human CD79A / CD79 Alpha
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纯化方法
- Protein G purified
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免疫原
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Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for this CD79a antibody. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Baboon, Monkey (93%), Bat, Pig (87%), Galago, Bovine (80%), Mouse (73%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG1 kappa
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应用备注
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Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)
Usage: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B-cell Ag receptor. CD79a first appears at pre B-cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. It is found in the majority of acute leukemias of B-cell precursors, lines and lymphomas, and in some myelomas. It is not present in myeloid or Tcell lines. CD79a antibody is generally used to complement CD20 mAb, especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This CD79a antibody will stain many of the same lymphomas as CD20 mAb, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is CD20 mAb. CD79a antibody also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well. ELISA: Order BSA-free format for coating. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C to 8°C.
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- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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别名
- CD79A
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背景
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Name/Gene ID: CD79A
Synonyms: CD79A, CD79a antigen, Ig-alpha, MB-1, MB-1 membrane glycoprotein, Surface IgM-associated protein, MB1 -
基因ID
- 973
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途径
- BCR Signaling
抗原
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