ANO1 抗体
Quick Overview for ANO1 抗体 (ABIN2738283)
抗原
See all ANO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human ANO1 / DOG1 / TMEM16A
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纯化方法
- Protein G purified
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免疫原
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Recombinant human TMEM16A / DOG1 protein.
Type of Immunogen: Recombinant protein -
亚型
- IgG1 kappa
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应用备注
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Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)
Usage: Expression of TMEM16A (DOG1) protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. TMEM16A is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for TMEM16A has been reported in 97.8 percent of scorable GIST's, including all c-kit negative GIST's. Overexpression has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha (PDGFR alpha) mutants that fail to express c-kit antigen. The overall sensitivity of TMEM16A and c-kit in GIST's is nearly identical: 94.4 % vs. 94.7 %. ELISA: Order BSA-free antibody format for coating. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C to 8°C.
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- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
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别名
- ANO1 / DOG1 / TMEM16A
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背景
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Name/Gene ID: ANO1
Synonyms: ANO1, Oral cancer overexpressed 2, Transmembrane protein 16A, ORAOV2, Anoctamin-1, DOG1, TAOS2, TMEM16A -
基因ID
- 55107
抗原
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