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ACTH 抗体 (AA 1-24)

This 小鼠 单克隆 antibody specifically detects ACTH in IHC, IF, FACS, ELISA, WB, IP 和 IHC (p). It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN2738117
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ACTH 抗体 (AA 1-24) (ABIN2738117)

抗原

See all ACTH 抗体
ACTH (Adrenocorticotropic hormone (ACTH))

适用

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人, 大鼠, 小鼠

宿主

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  • 1
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  • 1
小鼠

克隆类型

  • 130
  • 55
单克隆

标记

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This ACTH antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA, Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

AH26
  • 抗原表位

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    AA 1-24

    特异性

    Human ACTH

    纯化方法

    Protein G purified

    免疫原

    A synthetic peptide corresponding to aa1-24 of human ACTH.

    Type of Immunogen: Synthetic peptide

    亚型

    IgG1 kappa
  • 应用备注

    Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

    Usage: POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific post-translational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH (also called Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. Clone AH26 antibody is specific to Synacthen (aa 1-24 of ACTH) and does not react with CLIP (aa 17-39). ACTH is produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Specific antibody is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) that cause paraneoplastic syndromes by secreting ACTH. ELISA: Order BSA-free antibody format for coating.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2°C to 8°C.
  • 抗原

    ACTH (Adrenocorticotropic hormone (ACTH))

    别名

    ACTH

    物质类

    Hormone

    背景

    Name/Gene ID: ACTH

    Synonyms: ACTH

    途径

    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
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