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SOCS3 抗体

Cited in 1 publication. The 小鼠 单克隆 anti-SOCS3 antibody (Clone 3D3) (ABIN2732335) specifically detects SOCS3 in WB, IHC, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN2732335
发货至: 中国
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Quick Overview for SOCS3 抗体 (ABIN2732335)

抗原

See all SOCS3 抗体
SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SOCS3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

3D3
  • 产品特性

    Homo sapiens suppressor of cytokine signaling 3 (SOCS3)

    纯化方法

    Purified from mouse ascites fluids by affinity chromatography

    免疫原

    Full length human recombinant protein of human SOCS3 (NP_003946) produced in HEK293T cell.

    亚型

    IgG2a
  • 应用备注

    WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

    说明

    The concentration of the product may vary between diferrent lots.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5-1.0 mg/mL

    缓冲液

    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Lin, Wei, Tsai, Wu, Wu, Chen: "Glycosylation-dependent interaction between CD69 and S100A8/S100A9 complex is required for regulatory T-cell differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 5006-17, (2015) (PubMed).

  • 抗原

    SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

    别名

    SOCS3

    背景

    This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

    分子量

    24.6 kDa

    基因ID

    9021

    NCBI登录号

    NM_003955

    HGNC

    9021

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
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