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SAMHD1 抗体

There are 4+ publications for this product available. The 小鼠 单克隆 anti-SAMHD1 antibody is suitable to detect SAMHD1 in samples from 人, 小鼠, 大鼠, 猴 和 犬. It has been validated for WB, IHC, IF 和 FACS.
产品编号 ABIN2731372
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SAMHD1 抗体 (ABIN2731372)

抗原

See all SAMHD1 抗体
SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

适用

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人, 小鼠, 大鼠, 猴, 犬

宿主

  • 83
  • 11
小鼠

克隆类型

  • 65
  • 29
单克隆

标记

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This SAMHD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

3F5
  • 产品特性

    Homo sapiens SAM domain and HD domain 1 (SAMHD1)

    纯化方法

    Purified from mouse ascites fluids by affinity chromatography

    免疫原

    Full length human recombinant protein of human SAMHD1(NP_056289) produced in HEK293T cell.

    亚型

    IgG2b
  • 应用备注

    WB 1:200~500, IHC 1:150, IF 1:100, FLOW 1:100,

    说明

    The concentration of the product may vary between diferrent lots.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5-1.0 mg/mL

    缓冲液

    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Daddacha, Koyen, Bastien, Head, Dhere, Nabeta, Connolly, Werner, Madden, Daly, Minten, Whelan, Schlafstein, Zhang, Anand, Doronio, Withers, Shepard, Sundaram, Deng, Dynan, Wang, Bindra, Cejka et al.: "SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination. ..." in: Cell reports, Vol. 20, Issue 8, pp. 1921-1935, (2018) (PubMed).

    Oh, Ryoo, Park, Kim, Daly, Cho, Ahn: "A central role for PI3K-AKT signaling pathway in linking SAMHD1-deficiency to the type I interferon signature." in: Scientific reports, Vol. 8, Issue 1, pp. 84, (2018) (PubMed).

    Jáuregui, Landau: "DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1." in: Scientific reports, Vol. 8, Issue 1, pp. 4153, (2018) (PubMed).

    Wittmann, Behrendt, Eissmann, Volkmann, Thomas, Ebert, Cribier, Benkirane, Hornung, Bouzas, Gramberg: "Phosphorylation of murine SAMHD1 regulates its antiretroviral activity." in: Retrovirology, Vol. 12, pp. 103, (2015) (PubMed).

  • 抗原

    SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

    别名

    SAMHD1

    分子量

    72 kDa

    基因ID

    25939

    NCBI登录号

    NM_015474

    HGNC

    25939
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