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SAMHD1 抗体

This 小鼠 单克隆 antibody specifically detects SAMHD1 in WB, IF 和 FACS. It exhibits reactivity toward 人. It has been mentioned in 4+ publications
产品编号 ABIN2731369
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SAMHD1 抗体 (ABIN2731369)

抗原

See all SAMHD1 抗体
SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

适用

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宿主

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小鼠

克隆类型

  • 64
  • 26
单克隆

标记

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This SAMHD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

2D7
  • 产品特性

    Homo sapiens SAM domain and HD domain 1 (SAMHD1)

    纯化方法

    Purified from mouse ascites fluids by affinity chromatography

    免疫原

    Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell.

    亚型

    IgG2b
  • 应用备注

    WB 1:2000, IF 1:100, FLOW 1:100

    说明

    The concentration of the product may vary between diferrent lots.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5-1.0 mg/mL

    缓冲液

    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Jeong, Park, Ahn, Ahn: "Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1." in: Virology, Vol. 495, pp. 71-8, (2016) (PubMed).

    Hertoghs, van der Aar, Setiawan, Kootstra, Gringhuis, Geijtenbeek: "SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 9, pp. 4431-7, (2015) (PubMed).

    Pan, Pan, Weng, Zhao, Zhang, Wang, Lv, Jiang, Zheng, Xia: "Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 54, Issue 8, pp. 598-607, (2015) (PubMed).

    Zhang, Bloch, Nguyen, Kim, Landau: "SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e89558, (2014) (PubMed).

  • 抗原

    SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

    别名

    SAMHD1

    背景

    This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. COMPLETENESS: complete on the 3' end.

    分子量

    72 kDa

    基因ID

    25939

    NCBI登录号

    NM_015474

    HGNC

    25939
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