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SAMHD1 抗体

This 小鼠 单克隆 antibody specifically detects SAMHD1 in WB, IF 和 FACS. It exhibits reactivity toward 人 和 猴. It has been mentioned in 4+ publications
产品编号 ABIN2731368
发货至: 中国
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中国
北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SAMHD1 抗体 (ABIN2731368)

抗原

See all SAMHD1 抗体
SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

适用

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人, 猴

宿主

  • 83
  • 11
小鼠

克隆类型

  • 65
  • 29
单克隆

标记

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  • 1
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This SAMHD1 antibody is un-conjugated

应用范围

  • 71
  • 27
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  • 15
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  • 6
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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

1F6
  • 纯化方法

    Purified from mouse ascites fluids by affinity chromatography

    免疫原

    Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell.

    亚型

    IgG1
  • 应用备注

    WB 1:500~2000, IF 1:100, FLOW 1:100

    说明

    The concentration of the product may vary between diferrent lots.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5-1.0 mg/mL

    缓冲液

    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Hofmann, Vanwalscappel, Bloch, Landau: "TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes." in: Retrovirology, Vol. 13, Issue 1, pp. 83, (2017) (PubMed).

    Martin-Gayo, Buzon, Ouyang, Hickman, Cronin, Pimenova, Walker, Lichterfeld, Yu: "Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers." in: PLoS pathogens, Vol. 11, Issue 6, pp. e1004930, (2015) (PubMed).

    Tabler, Lucera, Haqqani, McDonald, Migueles, Connors, Tilton: "CD4+ memory stem cells are infected by HIV-1 in a manner regulated in part by SAMHD1 expression." in: Journal of virology, Vol. 88, Issue 9, pp. 4976-86, (2014) (PubMed).

    Zhang, Bloch, Nguyen, Kim, Landau: "SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e89558, (2014) (PubMed).

  • 抗原

    SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

    别名

    SAMHD1

    分子量

    72.0 kDa

    基因ID

    25939

    NCBI登录号

    NM_015474

    HGNC

    25939
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