RGS5 抗体
Quick Overview for RGS5 抗体 (ABIN2730835)
抗原
See all RGS5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens regulator of G-protein signaling 5 (RGS5), transcript variant 1
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human RGS5 (NP_003608) produced in HEK293T cell.
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亚型
- IgG1
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应用备注
- WB 1:2000, IHC 1:150, FLOW 1:100
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Lipid rafts are required for signal transduction by angiotensin II receptor type 1 in neonatal glomerular mesangial cells." in: Experimental cell research, Vol. 324, Issue 1, pp. 92-104, (2014) (PubMed).
: "Brain pericytes acquire a microglial phenotype after stroke." in: Acta neuropathologica, Vol. 128, Issue 3, pp. 381-96, (2014) (PubMed).
: "PKH26 staining defines distinct subsets of normal human colon epithelial cells at different maturation stages." in: PLoS ONE, Vol. 7, Issue 8, pp. e43379, (2012) (PubMed).
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: "Lipid rafts are required for signal transduction by angiotensin II receptor type 1 in neonatal glomerular mesangial cells." in: Experimental cell research, Vol. 324, Issue 1, pp. 92-104, (2014) (PubMed).
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- RGS5 (Regulator of G-Protein Signaling 5 (RGS5))
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别名
- RGS5
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背景
- This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
- 20.8 kDa
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基因ID
- 8490
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NCBI登录号
- NM_003617
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HGNC
- 8490
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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