RASSF1 抗体
Quick Overview for RASSF1 抗体 (ABIN2730552)
抗原
See all RASSF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human RASSF1 (NP_009113) produced in E.coli.
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亚型
- IgG1
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应用备注
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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别名
- RASSF1
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背景
- This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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分子量
- 38.6 kDa
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基因ID
- 11186
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NCBI登录号
- NM_007182
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HGNC
- 28844
抗原
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