PSMB9 抗体 (AA 21-219)
Quick Overview for PSMB9 抗体 (AA 21-219) (ABIN2729947)
抗原
See all PSMB9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 21-219
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产品特性
- Homo sapiens proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) (PSMB9)
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Human recombinant protein fragment corresponding to amino acids 21-219 of human PSMB9(NP_002791) produced in E.coli.
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亚型
- IgG2a
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应用备注
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- PSMB9 (Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9))
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别名
- PSMB9
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背景
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
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分子量
- 23.1 kDa
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基因ID
- 5698
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NCBI登录号
- NM_002800
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HGNC
- 5698
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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