电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

GDF15 抗体

GDF15 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 3C12 unconjugated
产品编号 ABIN2728532
发货至: 中国
  • 抗原 See all GDF15 抗体
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    适用
    • 87
    • 30
    • 23
    • 1
    • 1
    宿主
    • 86
    • 11
    • 2
    • 1
    小鼠
    克隆类型
    • 86
    • 13
    • 1
    单克隆
    标记
    • 51
    • 15
    • 9
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GDF15 antibody is un-conjugated
    应用范围
    • 85
    • 53
    • 36
    • 16
    • 13
    • 13
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
    产品特性
    Homo sapiens peptide deformylase (mitochondrial) (PDF), nuclear gene encoding mitochondrial protein
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinant protein of human PDF (NP_071736) produced in HEK293T cell.
    克隆位点
    3C12
    亚型
    IgG1
    Top Product
    Discover our top product GDF15 Primary Antibody
  • 应用备注
    WB 1:500, IF 1:100, FLOW 1:100
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    别名
    PDF (GDF15 产品)
    别名
    GDF15 antibody, GDF-15 antibody, MIC-1 antibody, MIC1 antibody, NAG-1 antibody, PDF antibody, PLAB antibody, PTGFB antibody, SBF antibody, growth differentiation factor 15 antibody, GDF15 antibody, Gdf15 antibody
    背景
    Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.
    分子量
    19.4 kDa
    基因ID
    64146
    NCBI登录号
    NM_022341
    HGNC
    64146
    途径
    SARS-CoV-2 Protein Interactome
You are here:
客服