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PDE10A 抗体

The 小鼠 单克隆 anti-PDE10A antibody is suitable to detect PDE10A in samples from 人. It has been validated for WB 和 FACS.
产品编号 ABIN2728473
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for PDE10A 抗体 (ABIN2728473)

抗原

See all PDE10A 抗体
PDE10A (phosphodiesterase 10A (PDE10A))

适用

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宿主

  • 20
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小鼠

克隆类型

  • 20
  • 7
单克隆

标记

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  • 2
  • 2
This PDE10A antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

4A10
  • 产品特性

    Homo sapiens phosphodiesterase 10A (PDE10A), transcript variant 2

    纯化方法

    Purified from mouse ascites fluids by affinity chromatography

    免疫原

    Full length human recombinant protein of human PDE10A (NP_006652) produced in HEK293T cell.

    亚型

    IgG1
  • 应用备注

    WB:1:500, FC:1:50

    说明

    The concentration of the product may vary between diferrent lots.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5-1.0 mg/mL

    缓冲液

    PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    PDE10A (phosphodiesterase 10A (PDE10A))

    别名

    PDE10A

    背景

    Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3'cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. There are 11 subtypes of PDEs, named PDE1-11, PDE4, 7 and 8 selectively degrade cAMP, PDE5, 6 and 9 selectively degrade cGMP and PDE1, 2, 3, 10 and 11 degrade both cyclic nucleotides. PDEs are expressed ubiquitously,with each subtype having a specific tissue distribution. These enzymes are involved in many signal transduction pathways and their functions include vascular smooth muscle proliferation and contraction, cardiac contractility,platelet aggregation, hormone secretion, immune cell activation, and they are involved in learning and memory.

    分子量

    88.4 kDa

    基因ID

    10846

    NCBI登录号

    NM_006661

    HGNC

    10846

    途径

    cAMP Metabolic Process
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