CCM2 抗体
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北京 101111
Quick Overview for CCM2 抗体 (ABIN2725241)
抗原
See all CCM2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens cerebral cavernous malformation 2 (CCM2), transcript variant 2
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human CCM2(NP_113631) produced in HEK293T cell.
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亚型
- IgG1
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anti-Cerebral Cavernous Malformation 2 (CCM2) (Internal Region) antibody
Verified CCM2 适用: 人, 大鼠 WB, IF, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-300) antibodyCCM2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-300) antibodyCCM2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 2-100) antibodyCCM2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) antibodyCCM2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444), (N-Term) antibodyCCM2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:2000, IHC 1:150, IF 1:100,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
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别名
- CCM2
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背景
- This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 48.7 kDa
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基因ID
- 83605
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NCBI登录号
- NM_031443
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HGNC
- 83605
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途径
- Cell-Cell Junction Organization
抗原
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