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- 抗原 See all CCM2 抗体
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CCM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 产品特性
- Homo sapiens cerebral cavernous malformation 2 (CCM2), transcript variant 2
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Full length human recombinant protein of human CCM2(NP_113631) produced in HEK293T cell.
- 克隆位点
- 2F9
- 亚型
- IgG1
- Top Product
- Discover our top product CCM2 Primary Antibody
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anti-Cerebral Cavernous Malformation 2 (CCM2) (Internal Region) antibody
Verified CCM2 适用: 人, 大鼠 WB, IF, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-300) antibodyCCM2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) antibodyCCM2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-300) antibodyCCM2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 2-100) antibodyCCM2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444), (N-Term) antibodyCCM2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:2000, IHC 1:150, IF 1:100,
- 说明
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The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
- 别名
- CCM2 (CCM2 产品)
- 背景
- This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 48.7 kDa
- 基因ID
- 83605
- NCBI登录号
- NM_031443
- HGNC
- 83605
- 途径
- Cell-Cell Junction Organization
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