ITM2B 抗体
Quick Overview for ITM2B 抗体 (ABIN2723906)
抗原
See all ITM2B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens integral membrane protein 2B (ITM2B)
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human ITM2B (NP_068839) produced in HEK293T cell.
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亚型
- IgG2a
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应用备注
- WB 1:2000, IHC 1:150, FLOW 1:100
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- ITM2B (Integral Membrane Protein 2B (ITM2B))
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别名
- ITM2B
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背景
- Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
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分子量
- 30.2 kDa
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基因ID
- 9445
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NCBI登录号
- NM_021999
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HGNC
- 9445
抗原
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