TNNI3 抗体
Quick Overview for TNNI3 抗体 (ABIN272322)
抗原
See all TNNI3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts equally with free cardiac Troponin I (cTnI) and cTnI forming complexes with other troponin components. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope located between amino acid residues 186 and 192 of cTnI. Cross-reacts with skeletal troponin I from human, rat and mouse.
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交叉反应 (详细)
- Also reacts to: skeletal
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纯化方法
- Protein A chromatography
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纯度
- > 90 % pure (SDS-PAGE)
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免疫原
- Free human cardiac troponin I
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 3.5mg/mL (Sigma protein assay kit)
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缓冲液
- PBS, pH 7.4 containing 0,09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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: "Re-programming of newt cardiomyocytes is induced by tissue regeneration." in: Journal of cell science, Vol. 119, Issue Pt 22, pp. 4719-29, (2007) (PubMed).
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: "Re-programming of newt cardiomyocytes is induced by tissue regeneration." in: Journal of cell science, Vol. 119, Issue Pt 22, pp. 4719-29, (2007) (PubMed).
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- TNNI3 (Cardiac Troponin I (TNNI3))
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别名
- Cardiac Troponin I
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背景
- Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.Synonyms: TNNC1, TNNI3
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基因ID
- 7137
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NCBI登录号
- NP_000354
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UniProt
- P19429
抗原
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