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TNNI3 抗体

This anti-TNNI3 antibody is a 小鼠 单克隆 antibody detecting TNNI3 in WB 和 EIA. Suitable for 人, 小鼠, Cow, 兔, 鱼, Amphibian 和 小鸡. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN272322
发货至: 中国

Quick Overview for TNNI3 抗体 (ABIN272322)

抗原

See all TNNI3 抗体
TNNI3 (Cardiac Troponin I (TNNI3))

适用

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人, 小鼠, Cow, 兔, 鱼, Amphibian, 小鸡

宿主

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小鼠

克隆类型

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单克隆

标记

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This TNNI3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

C5
  • 特异性

    This antibody reacts equally with free cardiac Troponin I (cTnI) and cTnI forming complexes with other troponin components. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope located between amino acid residues 186 and 192 of cTnI. Cross-reacts with skeletal troponin I from human, rat and mouse.

    交叉反应 (详细)

    Also reacts to: skeletal

    纯化方法

    Protein A chromatography

    纯度

    > 90 % pure (SDS-PAGE)

    免疫原

    Free human cardiac troponin I

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    3.5mg/mL (Sigma protein assay kit)

    缓冲液

    PBS, pH 7.4 containing 0,09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • Laube, Heister, Scholz, Borchardt, Braun: "Re-programming of newt cardiomyocytes is induced by tissue regeneration." in: Journal of cell science, Vol. 119, Issue Pt 22, pp. 4719-29, (2007) (PubMed).

  • 抗原

    TNNI3 (Cardiac Troponin I (TNNI3))

    别名

    Cardiac Troponin I

    背景

    Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.Synonyms: TNNC1, TNNI3

    基因ID

    7137

    NCBI登录号

    NP_000354

    UniProt

    P19429
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