HSPB8 抗体
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北京 101111
Quick Overview for HSPB8 抗体 (ABIN2723116)
抗原
See all HSPB8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens heat shock 22 kDa protein 8 (HSPB8)
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human HSPB8(NP_055180) produced in HEK293T cell.
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亚型
- IgG2a
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应用备注
- WB 1:500~2000, IF 1:100, FLOW 1:100
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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别名
- HSPB8
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背景
- The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
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分子量
- 21.4 kDa
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基因ID
- 26353
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NCBI登录号
- NM_014365
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HGNC
- 26353
抗原
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