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HOXA7 抗体

This anti-HOXA7 antibody is a 兔 多克隆 antibody detecting HOXA7 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN272304
发货至: 中国

Quick Overview for HOXA7 抗体 (ABIN272304)

抗原

See all HOXA7 抗体
HOXA7 (Homeobox A7 (HOXA7))

适用

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人, 小鼠, 大鼠

宿主

  • 35
  • 4

克隆类型

  • 36
  • 3
多克隆

标记

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This HOXA7 antibody is un-conjugated

应用范围

  • 30
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  • 11
  • 2
  • 1
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  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of Hox-A7 protein. (region surrounding Gly127)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    HOXA7 (Homeobox A7 (HOXA7))

    别名

    HOXA7 / HOX1A

    背景

    Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxA1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor which has been shown to play important roles in cell differentiation and embryogenesis. HoxA1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, HoxA2 is expressed in the mesenchyme and epithelial cells of the palate, however its expression is restricted to the tips of the growing palatal shelves. HoxA2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, HoxA2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. HoxA7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. HoxA7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.Synonyms: Homeobox protein Hox-A7, Hox-1A

    分子量

    approx. 25 kDa

    基因ID

    3204

    NCBI登录号

    NP_008827

    UniProt

    P31268
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