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Cadherin 13 抗体

CDH13 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272293
发货至: 中国
  • 抗原 See all Cadherin 13 (CDH13) 抗体
    Cadherin 13 (CDH13)
    适用
    人, 小鼠, 大鼠
    宿主
    • 95
    • 4
    • 2
    • 1
    克隆类型
    • 90
    • 12
    多克隆
    标记
    • 43
    • 14
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cadherin 13 antibody is un-conjugated
    应用范围
    • 69
    • 52
    • 46
    • 19
    • 14
    • 13
    • 12
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of T-Cadherin protein. (region surrounding Met352)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product CDH13 Primary Antibody
  • 应用备注
    ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Cadherin 13 (CDH13)
    别名
    Cadherin-13 (CDH13 产品)
    别名
    CDH13 antibody, CDHH antibody, P105 antibody, 4932416G01Rik antibody, Cdht antibody, T-cadherin antibody, Tcad antibody, cadherin 13 antibody, CDH13 antibody, Cdh13 antibody
    背景
    The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin, also designated heartcadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cells lines. Evidence suggests that decreased levels of T-cadherin indicate a progression in breast malignancies.Synonyms: CDH13, CDHH, Cadherin H, Cadherin T, H-Cadherin, Heart cadherin, P105, T-Cadherin, Truncated cadherin
    分子量
    approx. 78 kDa
    基因ID
    1012
    NCBI登录号
    NP_001248
    UniProt
    P55290
    途径
    EGFR Signaling Pathway, Cell-Cell Junction Organization
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