Cadherin 13 抗体
Quick Overview for Cadherin 13 抗体 (ABIN272293)
抗原
See all Cadherin 13 (CDH13) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of T-Cadherin protein. (region surrounding Met352)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Cadherin 13 (CDH13) antibody
CDH13 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 23-133) antibodyCDH13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 1-713) antibodyCDH13 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (Internal Region) antibodyCDH13 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 301-400) antibodyCDH13 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 1-713) antibodyCDH13 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 179-366) antibodyCDH13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 478-690) antibodyCDH13 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 589-617), (C-Term) antibodyCDH13 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 146-174), (N-Term) antibodyCDH13 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Cadherin 13 (CDH13)
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别名
- Cadherin-13
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背景
- The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin, also designated heartcadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cells lines. Evidence suggests that decreased levels of T-cadherin indicate a progression in breast malignancies.Synonyms: CDH13, CDHH, Cadherin H, Cadherin T, H-Cadherin, Heart cadherin, P105, T-Cadherin, Truncated cadherin
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分子量
- approx. 78 kDa
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基因ID
- 1012
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NCBI登录号
- NP_001248
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UniProt
- P55290
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途径
- EGFR Signaling Pathway, Cell-Cell Junction Organization
抗原
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