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ADD3 抗体

This 兔 多克隆 antibody specifically detects ADD3 in WB, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN272287
发货至: 中国
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Quick Overview for ADD3 抗体 (ABIN272287)

抗原

See all ADD3 抗体
ADD3 (Adducin 3 (Gamma) (ADD3))

适用

  • 36
  • 18
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  • 3
  • 2
  • 2
  • 1
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人, 小鼠, 大鼠

宿主

  • 35
  • 1

克隆类型

  • 36
多克隆

标记

  • 24
  • 2
  • 1
  • 1
  • 1
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This ADD3 antibody is un-conjugated

应用范围

  • 28
  • 16
  • 8
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  • 4
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Adducin γ protein. (region surrounding Pro452)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    ADD3 (Adducin 3 (Gamma) (ADD3))

    别名

    gamma-Adducin (ADD3)

    背景

    Adducins are a family of cytoskeleton proteins encoded by three genes (α, β and γ). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and adducins are central in the cortical actin network organization. Adducin α is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin α and Adducin γ is ubiquitous in contrast to the restricted expression of Adducin β. Adducin β is expressed at high levels in brain andhematopoietic tissues, such as bone marrow in humans, and spleen in mice.Synonyms: ADDL, Adducin 3, Adducin-like protein 70

    分子量

    approx. 82 kDa

    基因ID

    120

    NCBI登录号

    NP_001112

    UniProt

    Q9UEY8
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