CD83 抗体
Quick Overview for CD83 抗体 (ABIN272283)
抗原
See all CD83 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of CD83 protein. (region surrounding Pro130)
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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应用备注
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ELISA: 1/1000approx. 1/5000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C one month or (in aliquots) at -20 °C for longer.
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- CD83
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别名
- CD83
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背景
- CD83 is a heavily glycosylated membrane protein of the immunoglobulin (Ig) superfamily that is expressed in mature dendritic cells, Langerhans cells and interdigitating reticulum cells within lymphoid tissues. Structurally, CD83 resembles other Ig superfamily members, which have an extracellular V-type Ig-like domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 expression is used as a marker for mature, antigen presenting dendritic cells that are capable of generating tumor-specific T cell immunity, a phenotype with implications as an anticancer vaccine. CD83-IgG1(fc) chimera studies indicate that CD83 is a sialic acid-binding, Ig-like lectin (Siglec) adhesion molecule that is involved in cell adhesion/signaling by hosting dendritic cell interactions with monocytes and CD8+ T cells.Synonyms: B-cell activation protein, Cell surface protein HB15, HB15
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分子量
- approx. 23, 45 kDa
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基因ID
- 9308
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NCBI登录号
- NP_001035370
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UniProt
- Q01151
抗原
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