YWHAB 抗体
Quick Overview for YWHAB 抗体 (ABIN272264)
抗原
See all YWHAB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of 14-3-3 beta protein. (region surrounding Gln69)
-
交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
-
-
anti-14-3-3 alpha + beta (YWHAB) (AA 1-246) antibody
YWHAB 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 1-246) antibodyYWHAB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 5B5G10 unconjugated
anti-14-3-3 alpha + beta (YWHAB) (Center) antibodyYWHAB 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 1-246) antibodyYWHAB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 1-141) antibodyYWHAB 适用: 人, 斑马鱼 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 34-221) antibodyYWHAB 适用: 人, 斑马鱼 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (pSer58) antibodyYWHAB 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 56-85), (N-Term) antibodyYWHAB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4062 unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 217-246), (C-Term) antibodyYWHAB 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4064 unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 51-150) antibodyYWHAB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- YWHAB (14-3-3 alpha + beta (YWHAB))
-
别名
- 14-3-3 Protein beta/alpha
-
背景
- 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.Synonyms: KCIP-1, Protein 1054, Protein kinase C inhibitor protein 1, YWHAB
-
分子量
- approx. 28 kDa
-
基因ID
- 7529
-
NCBI登录号
- NP_003395
-
UniProt
- P31946
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location
抗原
-
