YBX2 抗体
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Quick Overview for YBX2 抗体 (ABIN272262)
抗原
See all YBX2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of MSY2 protein. (region surrounding Gly311)
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交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- YBX2 (Y Box Binding Protein 2 (YBX2))
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别名
- YBX2
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背景
- Contrin (MSY2 in mouse) and YB-2 (MSY3/4 in mouse) belong to the Y-box family of multifunctional proteins that regulate both transcription and translation.Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins. The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing arginine clusters and aromatic residues. MSY2 (Contrin) is a expressed in testis and ovary, where it may repress translation of parental mRNA. The gene encoding human Contrin maps to chromosome 17p11.2-13.1. MSY3/4 (YB-2) is also known as DNA binding protein A and is highly expressed in testis, heart and muscle. Contrin and YB-2 bind to the consensus sequence 5'-UCCAUCA-3' contained in the Y-box element.Synonyms: CSDA3, Contrin, DBPC, DNA-binding protein C, Germ cell-specific Y-box-binding protein, MSY2, MSY2 homolog, Y-box-binding protein 2
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分子量
- approx. 38 kDa
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基因ID
- 51087
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NCBI登录号
- NP_057066
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UniProt
- Q9Y2T7
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途径
- Chromatin Binding
抗原
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