MLX 抗体
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北京 101111
Quick Overview for MLX 抗体 (ABIN272258)
抗原
See all MLX 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Mlx protein. (region surrounding Gln136)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-MAX-Like Protein X (MLX) (AA 125-151) antibody
MLX 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22641 unconjugated
anti-MAX-Like Protein X (MLX) (Internal Region) antibodyMLX 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (C-Term) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 山羊, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (C-Term) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 山羊, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (N-Term) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 山羊, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (AA 1-244) antibodyMLX 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1C3 unconjugated
anti-MAX-Like Protein X (MLX) (AA 1-244) antibodyMLX 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (AA 201-250) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 山羊, 马, 兔, 斑马鱼, 猴, Hamster, Bat, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (Center) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (AA 1-214) antibodyMLX 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- MLX (MAX-Like Protein X (MLX))
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别名
- Max-Like Protein X
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背景
- Max is a nuclear localized bHLH-Zip protein that forms homodimers or heterodimers with Myc family members, including Myc, Mad 1, Mad 3, Mad 4, Mxi1 and Mnt (or Rox). These dimers bind to the E-box sequence CACGTG in order to regulate cell growth, proliferation and apoptosis. Mlx (Max-like protein X) is a bHLH-Zip protein that is structurally and functionally related to Max. Like Max, Mlx is broadly expressed in many tissues and has a long half-life. Mlx also forms homodimers or heterodimers with members of the Myc family, specifically Mad 1, Mad 4 and Rox, and members of the Mondo family, to repress or activate transcription from CACGTG E-boxes. MondoA forms weak homodimers and preferentially forms heterodimers with Mlx. The MondoA/Mlx complex is primarily localized to the cytoplasm, but will translocate to the nucleus in response to leptomycin B. Mlx can also dimerize with WBSCR14, a protein involved in Williams-Beuren syndrome (WBS), to repress E-box transcription, which provides further evidence that Mlx is a critical element in a transcription factor network.Synonyms: BigMax protein, MLX, Max-like bHLHZip protein, TCFL4, Transcription factor-like protein 4
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分子量
- approx. 33 kDa
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基因ID
- 6945
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NCBI登录号
- NP_733752
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UniProt
- Q9UH92
抗原
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