HMG20B 抗体
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北京 101111
Quick Overview for HMG20B 抗体 (ABIN272257)
抗原
See all HMG20B 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of BRAF35 protein. (region surrounding Thr29)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-High Mobility Group 20B (HMG20B) (AA 1-109) antibody
HMG20B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-High Mobility Group 20B (HMG20B) (AA 1-317) antibodyHMG20B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) antibodyHMG20B 适用: 人 WB, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (AA 1-317) antibodyHMG20B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (N-Term) antibodyHMG20B 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (N-Term) antibodyHMG20B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (N-Term) antibodyHMG20B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (AA 1-213) antibodyHMG20B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (AA 27-213) antibodyHMG20B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (N-Term) antibodyHMG20B 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- HMG20B (High Mobility Group 20B (HMG20B))
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别名
- SMARCE1-Related Protein
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背景
- The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45 % of families with high incidence of breast cancer and at least 80 % of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a 20 kDa complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesinlike coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.Synonyms: BRAF35, BRCA2-associated factor 35, HMG box-containing protein 20B, HMG domain-containing protein 2, HMG domain-containing protein HMGX2, HMG20B, HMGX2, HMGXB2, SMARCE1R, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related, Sox-like transcriptional factor, Structural DNA-binding protein BRAF35
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分子量
- approx. 36 kDa
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基因ID
- 10362
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NCBI登录号
- NP_006330
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UniProt
- Q9P0W2
抗原
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