TINF2 抗体
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Quick Overview for TINF2 抗体 (ABIN272251)
抗原
See all TINF2 (TIN2) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of TIN2 protein. (region surrounding Val94)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-TERF1 Interacting Nuclear Factor 2 (TIN2) (AA 256-354) antibody
TIN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G11 unconjugated
anti-TERF1 Interacting Nuclear Factor 2 (TIN2) (AA 1-451) antibodyTIN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TERF1 Interacting Nuclear Factor 2 (TIN2) antibodyTIN2 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TERF1 Interacting Nuclear Factor 2 (TIN2) (AA 256-354) antibodyTIN2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-TERF1 Interacting Nuclear Factor 2 (TIN2) (AA 210-451) antibodyTIN2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TERF1 Interacting Nuclear Factor 2 (TIN2) antibodyTIN2 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 5G11 unconjugated Recombinant Antibody
anti-TERF1 Interacting Nuclear Factor 2 (TIN2) antibodyTIN2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-TERF1 Interacting Nuclear Factor 2 (TIN2) (C-Term) antibodyTIN2 适用: 人, Cow, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TERF1 Interacting Nuclear Factor 2 (TIN2) (AA 202-451) antibodyTIN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TERF1 Interacting Nuclear Factor 2 (TIN2) antibodyTIN2 适用: 人 WB 宿主: 兔 Monoclonal 24GB2450 unconjugated Recombinant Antibody
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
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别名
- TINF2 / TIN2
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背景
- Telomeres are DNA-protein structures that protect the ends of linear chromosomes and help maintain genomic stability and cell phenotype. Mammalian telomeric proteins consist of TRF1 (telomeric repeat binding factor), TRF2, tankyrase, and TIN2, which have no recognized orthologs in the budding yeast, Saccharomyces cerevisiae, and RAP1, which is an ortholog to the yeast telomeric protein scRap1. Like scRap1, mammalian RAP1 regulates telomere elongation. RAP1 interacts with two proteins, Rif1 and Rif2, which contribute to telomere length homeostasis. Unlike scRap1, which binds telomeric DNA directly, RAP1 is recruited to telomeres by TRF2. The functional and structural similarities of scRap1 to mammalian RAP1 suggest that the budding yeast preserved RAP1 at telomeres, but lost the TRF component. The telomeric protein TRF1 requires TIN2 to control telomere length in human cells.Synonyms: TERF1-interacting nuclear factor 2, TRF1-interacting nuclear protein 2
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分子量
- approx. 53 kDa
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基因ID
- 26277
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NCBI登录号
- NP_001092744
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UniProt
- Q9BSI4
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途径
- Cell Division Cycle, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
抗原
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