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E2F2 抗体

This 兔 多克隆 antibody specifically detects E2F2 in WB 和 IHC (p). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN272230
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for E2F2 抗体 (ABIN272230)

抗原

See all E2F2 抗体
E2F2 (E2F Transcription Factor 2 (E2F2))

适用

  • 69
  • 49
  • 26
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 62
  • 7

克隆类型

  • 46
  • 23
多克隆

标记

  • 36
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
This E2F2 antibody is un-conjugated

应用范围

  • 51
  • 19
  • 11
  • 11
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of E2F-2 protein. (region surrounding Lys236)

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    E2F2 (E2F Transcription Factor 2 (E2F2))

    别名

    E2F2

    背景

    The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcription regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.Synonyms: E2F transcription factor 2, E2F-2, Transcription factor E2F2

    分子量

    approx. 48 kDa

    基因ID

    1870

    NCBI登录号

    NP_004082

    UniProt

    Q14209

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
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