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LTA 抗体

The 兔 多克隆 anti-LTA antibody is suitable to detect LTA. It has been validated for WB 和 EIA.
产品编号 ABIN272216
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LTA 抗体 (ABIN272216)

抗原

See all LTA 抗体
LTA (Lymphotoxin-alpha (LTA))

宿主

  • 67
  • 29
  • 5
  • 1

克隆类型

  • 68
  • 33
  • 1
多克隆

标记

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This LTA antibody is un-conjugated

应用范围

  • 67
  • 36
  • 29
  • 24
  • 18
  • 10
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of LT-beta protein. (region surrounding Val211)

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    LTA (Lymphotoxin-alpha (LTA))

    别名

    TNF-beta / Lymphotoxin-alpha

    物质类

    Chemical

    背景

    Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-alpha, also known as TNF-beta) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. LT-beta (lymphotaxin-beta or tumor necrosis factor C) is a type II membrane protein with significant homology to TNF, LT-alpha, and the ligand for the CD40 receptor. LT-alpha is present on the surface of activated T, B, and LAK cells as a complex with the 33 kda glycoprotein, LT-beta. LT-beta, also expressed by active lymphocytes, forms a heterotrimer with LT-a on the cell surface and anchors LT-alpha to the cell surface. A TNF receptor-related protein, the LT-beta receptor (also known as TNFC receptor), is the human receptor for the LT-alpha/LT-beta heterotrimer. There are two LT-beta isoforms expressed in human lymphoid cell lines and non-Hodgkin's lymphomas. The gene which encodes LT-beta maps to the major histocompatibility complex region on human chromosome 6p21.3.Synonyms: LT-alpha, LTA, TNFB, TNFSF1, Tumor necrosis factor ligand superfamily member 1

    分子量

    approx. 22 kDa

    基因ID

    4049

    NCBI登录号

    NP_000586

    UniProt

    P01374

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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