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SRY 抗体

SRY 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272215
发货至: 中国
  • 抗原 See all SRY 抗体
    SRY (Sex Determining Region Y (SRY))
    适用
    • 26
    • 13
    • 2
    • 1
    • 1
    宿主
    • 32
    • 9
    克隆类型
    • 34
    • 7
    多克隆
    标记
    • 25
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SRY antibody is un-conjugated
    应用范围
    • 25
    • 21
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of SRY protein. (region surrounding Leu80)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product SRY Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    SRY (Sex Determining Region Y (SRY))
    别名
    SRY / TDF (SRY 产品)
    别名
    SRXX1 antibody, SRXY1 antibody, TDF antibody, TDY antibody, SRYGENE antibody, Sry1 antibody, Sry3BI antibody, Tdf antibody, Tdy antibody, SRY antibody, sex determining region Y antibody, sex determining region of Chr Y antibody, SRY antibody, Sry antibody
    背景
    SRY (sex-determining region Y protein) is a transcriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females.Synonyms: Sex-determining region Y protein, Testis-determining factor
    分子量
    approx. 37 kDa
    基因ID
    100130809
    NCBI登录号
    NP_003131
    UniProt
    Q05066
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