SRY 抗体
Quick Overview for SRY 抗体 (ABIN272215)
抗原
See all SRY 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of SRY protein. (region surrounding Leu80)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Sex Determining Region Y (SRY) antibody
SRY 适用: 人 WB 宿主: 小鼠 Monoclonal 1H10 unconjugated
anti-Sex Determining Region Y (SRY) (AA 1-204) antibodySRY 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sex Determining Region Y (SRY) (AA 52-82) antibodySRY 适用: 人 WB 宿主: 兔 Polyclonal RB53824 unconjugated
anti-Sex Determining Region Y (SRY) (AA 1-204) antibodySRY 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Sex Determining Region Y (SRY) (Internal Region) antibodySRY 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sex Determining Region Y (SRY) antibodySRY 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-Sex Determining Region Y (SRY) (Internal Region) antibodySRY 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sex Determining Region Y (SRY) (AA 81-112) antibodySRY 适用: 人 WB 宿主: 兔 Polyclonal RB53826 unconjugated
anti-Sex Determining Region Y (SRY) (C-Term) antibodySRY 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- SRY (Sex Determining Region Y (SRY))
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别名
- SRY / TDF
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背景
- SRY (sex-determining region Y protein) is a transcriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females.Synonyms: Sex-determining region Y protein, Testis-determining factor
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分子量
- approx. 37 kDa
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基因ID
- 100130809
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NCBI登录号
- NP_003131
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UniProt
- Q05066
抗原
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