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HNRNPF 抗体

The 兔 多克隆 anti-HNRNPF antibody (ABIN272205) specifically detects HNRNPF in WB 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN272205
发货至: 中国
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Quick Overview for HNRNPF 抗体 (ABIN272205)

抗原

See all HNRNPF 抗体
HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))

适用

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人, 小鼠, 大鼠

宿主

  • 49
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克隆类型

  • 49
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多克隆

标记

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This HNRNPF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 特异性

    This antibody detects endogenous levels of hnRNP F protein. (region surrounding Tyr47)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/5000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))

    别名

    HnRNP-F / HNRNPF

    背景

    Heterogeneous Nuclear Ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to pre-mRNA processing and transport, and also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. hnRNP complexes are the major constituents of the spliceosome and in particular, the hnRNP A1 protein is one of the major premRNA/mRNA binding proteins and also one of the most abundant proteins in the nucleus. hnRNP A1 and A2/B1 regulate the processing of pre-mRNA by directly antagonizing the association of various splicing factors and by influencing the splice site selection on pre-mRNA. The majority of hnRNP proteins components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm. Most hnRNP proteins, including hnRNP C1 and C2, contain one or more RNA binding domains and are implicated in the processing of pre-mRNA. hnRNPs F and H are largely related factors that preferentially associate with poly(rG) regions on RNA.Synonyms: HNRPF, Heterogeneous nuclear ribonucleoprotein F, Nucleolin-like protein mcs94-1

    分子量

    approx. 48 kDa

    基因ID

    3185

    NCBI登录号

    NP_001091674

    UniProt

    P52597
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