CBX5 抗体
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- 抗原 See all CBX5 抗体
- CBX5 (Chromobox Homolog 5 (CBX5))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBX5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of HP1-alpha/CBX5 protein. (region surrounding Lys69)
- 交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
- 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product CBX5 Primary Antibody
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anti-Chromobox Homolog 5 (CBX5) antibody
CBX5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (Internal Region) antibodyVerified CBX5 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 1B10B2 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E11-3A10 unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 7B6 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 30-137) antibodyCBX5 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000-1/20000. Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CBX5 (Chromobox Homolog 5 (CBX5))
- 别名
- CBX5 (CBX5 产品)
- 别名
- HP1 antibody, HP1A antibody, id:ibd2026 antibody, wu:fc63e02 antibody, wu:fe47g12 antibody, wu:fi03h05 antibody, zgc:158601 antibody, CBX5 antibody, cbx5 antibody, MGC64354 antibody, 2610029O15Rik antibody, C75991 antibody, Hp1a antibody, Hp1alpha antibody, chromobox 5 antibody, chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody, chromobox 5 S homeolog antibody, CBX5 antibody, cbx5 antibody, Cbx5 antibody, cbx5.S antibody
- 背景
- Chromatin assembly factor-1 (CAF-1) is a multisubunit protein complex that comprises three polypeptide subunits known as p150, p60, and p48. CAF-1 is a nucleosome assembly factor that deposits newly synthesized and acetylated histones H3/H4 into nascent chromatin during DNA replication. The p150 subunit of CAF-1 also supports the maintenance of heterochromatin, which requires the synthesis of both new histones and heterochromatin proteins and their orderly assembly during DNA replication. Heterochromatin is characterized as densely coiled chromatin that generally replicates late during S phase, has a low gene density, and contains large blocks of repetitive DNA that is relatively inaccessible to DNA-modifying reagents. In late S phase, p150 directly associates with heterochromatin associated proteins 1 (HP1), HP1α, HP1β and HP1γ. As cells prepare for mitosis, CAF-1 p150 and some HP1 progressively dissociate from heterochromatin, coinciding with the phosphorylation of histone H3. The HP1 proteins reassociate with chromatin at the end of mitosis, as histone H3 is dephosphorylated.Synonyms: Chromobox protein homolog 5, HP1 alpha, HP1-alpha, HP1A, Heterochromatin protein 1 homolog alpha, p25
- 分子量
- approx. 22 kDa
- 基因ID
- 23468
- NCBI登录号
- NP_001120793
- UniProt
- P45973
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