CBX5 抗体
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北京 101111
Quick Overview for CBX5 抗体 (ABIN272193)
抗原
See all CBX5 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of HP1-alpha/CBX5 protein. (region surrounding Lys69)
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交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Chromobox Homolog 5 (CBX5) (Internal Region) antibody
Verified CBX5 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1B10B2 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3A11F8 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E11-3A10 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 8G6 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000-1/20000. Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CBX5 (Chromobox Homolog 5 (CBX5))
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别名
- CBX5
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背景
- Chromatin assembly factor-1 (CAF-1) is a multisubunit protein complex that comprises three polypeptide subunits known as p150, p60, and p48. CAF-1 is a nucleosome assembly factor that deposits newly synthesized and acetylated histones H3/H4 into nascent chromatin during DNA replication. The p150 subunit of CAF-1 also supports the maintenance of heterochromatin, which requires the synthesis of both new histones and heterochromatin proteins and their orderly assembly during DNA replication. Heterochromatin is characterized as densely coiled chromatin that generally replicates late during S phase, has a low gene density, and contains large blocks of repetitive DNA that is relatively inaccessible to DNA-modifying reagents. In late S phase, p150 directly associates with heterochromatin associated proteins 1 (HP1), HP1α, HP1β and HP1γ. As cells prepare for mitosis, CAF-1 p150 and some HP1 progressively dissociate from heterochromatin, coinciding with the phosphorylation of histone H3. The HP1 proteins reassociate with chromatin at the end of mitosis, as histone H3 is dephosphorylated.Synonyms: Chromobox protein homolog 5, HP1 alpha, HP1-alpha, HP1A, Heterochromatin protein 1 homolog alpha, p25
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分子量
- approx. 22 kDa
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基因ID
- 23468
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NCBI登录号
- NP_001120793
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UniProt
- P45973
抗原
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