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FRK 抗体

The 兔 多克隆 anti-FRK antibody (ABIN272190) specifically detects FRK in WB, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN272190
发货至: 中国
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Quick Overview for FRK 抗体 (ABIN272190)

抗原

See all FRK 抗体
FRK (Fyn-Related Kinase (FRK))

适用

  • 47
  • 37
  • 32
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 63
  • 7
  • 1

克隆类型

  • 65
  • 6
多克隆

标记

  • 40
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This FRK antibody is un-conjugated

应用范围

  • 54
  • 30
  • 21
  • 13
  • 13
  • 8
  • 7
  • 5
  • 5
  • 3
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Rak protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    FRK (Fyn-Related Kinase (FRK))

    别名

    FRK / PTK5

    背景

    Src is the human homolog of the v-src gene of the Rous sarcoma virus, also known as avian sarcoma virus or ASV. Src is the first proto-oncogenic nonreceptor tyrosine kinase characterized in human. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility, and adhesion. Src-family kinases contain an amino terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Frk (Rak) is an epithelial tissue-specific kinase. The human Rak gene maps to chromosome 6q21-q22.3 and encodes a 505 amino acid protein.Synonyms: FYN-related kinase, Nuclear tyrosine protein kinase RAK, Protein-tyrosine kinase 5, RAK, Tyrosine-protein kinase FRK

    分子量

    approx. 55 kDa

    基因ID

    2444

    NCBI登录号

    NP_002022

    UniProt

    P42685
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