GRK5 抗体
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Quick Overview for GRK5 抗体 (ABIN272181)
抗原
See all GRK5 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GRK5 protein. (region surrouding Gln382)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (AA 371-590) antibody
GRK5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (AA 559-590), (C-Term) antibodyGRK5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB0903 unconjugated
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (AA 393-429), (C-Term) antibodyGRK5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) antibodyGRK5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (Internal Region) antibodyGRK5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (AA 406-590) antibodyGRK5 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (Internal Region) antibodyGRK5 适用: 人, 小鼠, 大鼠, Cow, 马, 小鸡, 猴, Pig, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (N-Term) antibodyGRK5 适用: 人, Cow, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (Internal Region) antibodyGRK5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (AA 290-339) antibodyGRK5 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 豚鼠, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))
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别名
- GPRK5
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背景
- Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonistmediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first are the second messenger-regulated kinases such as c-AMP dependent protein kinase A and protein kinase C. The second are the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase, GRK 1, two forms of β-adrenergic receptor kinase, GRK 2 (βARK, βARK1) and GRK 3 (βARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.Synonyms: G protein-coupled receptor kinase 5, GRK5
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分子量
- approx. 68 kDa
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基因ID
- 2869
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NCBI登录号
- NP_005299
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UniProt
- P34947
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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