EGR2 抗体
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Quick Overview for EGR2 抗体 (ABIN272177)
抗原
See all EGR2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Egr-2 protein. (region surrounding Arg409)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Early Growth Response 2 (EGR2) (AA 147-403) antibody
EGR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 2 (EGR2) (C-Term) antibodyEGR2 适用: 人, 小鼠, 大鼠, 马, Pig, Cow, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 2 (EGR2) (Internal Region) antibodyVerified EGR2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Early Growth Response 2 (EGR2) (AA 397-446) antibodyEGR2 适用: 人, 小鼠, 马, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 2 (EGR2) (AA 156-476) antibodyEGR2 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Early Growth Response 2 (EGR2) (AA 217-293) antibodyEGR2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G5 unconjugated
anti-Early Growth Response 2 (EGR2) (AA 156-476) antibodyEGR2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-Early Growth Response 2 (EGR2) (AA 1-476) antibodyEGR2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Early Growth Response 2 (EGR2) (AA 42-245) antibodyEGR2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 2 (EGR2) antibodyEGR2 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- EGR2 (Early Growth Response 2 (EGR2))
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别名
- EGR2
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背景
- Egr proteins function in transcription regulatory activities surrounding cellular growth, differentiation and function. The deduced amino acid sequences of human Egr-2 and mouse Egr-1 are 92 % identical in the zinc finger region but show no homology elsewhere. Egr-2 is a sequence-specific DNA-binding transcription factor that binds two specific DNA sites located in the promoter region of HoxA4 and localizes to the nucleus. Defects in the Egr-2 protein are a cause of congenital hypomyelination neuropathy (CHN). CHN is characterized clinically by early onset of hypotonia, areflexia, distal muscle weakness and very slow nerve conduction velocities. Mutations in the gene that encodes Egr-2 (EGR2) also cause of Dejerine-Sottas syndrome (DSS), which is also known as Dejerine-Sottas neuropathy (DSN) or hereditary motor and sensory neuropathy III (HMSN3). DSS patients exhibit severe early onset motor and sensory neuropathy with very slow nerve conduction velocities and elevated cerebrospinal fluid protein concentrations.Synonyms: AT591, EGR-2, Early growth response protein 2, KROX20, Krox 20, Zinc finger protein Krox-20
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分子量
- approx. 50 kDa
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基因ID
- 1959
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NCBI登录号
- NP_000390
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UniProt
- P11161
抗原
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