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HOXB9 抗体

This 兔 多克隆 antibody specifically detects HOXB9 in WB 和 IHC (p). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN272173
发货至: 中国
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Quick Overview for HOXB9 抗体 (ABIN272173)

抗原

See all HOXB9 抗体
HOXB9 (Homeobox B9 (HOXB9))

适用

  • 54
  • 23
  • 9
  • 8
  • 7
  • 7
  • 5
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
人, 小鼠

宿主

  • 48
  • 5
  • 1

克隆类型

  • 40
  • 14
多克隆

标记

  • 33
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HOXB9 antibody is un-conjugated

应用范围

  • 46
  • 19
  • 13
  • 12
  • 11
  • 8
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Hox-B9 protein. (region surrounding Arg237)

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    HOXB9 (Homeobox B9 (HOXB9))

    别名

    HOXB9 / HOX2E

    背景

    The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Themammalian Hox gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. Hox genes that occupy the same relative position along the 5' to 3' coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent Hox genes on the same chromosome. In mice, the HoxB cluster contains HoxB1 to HoxB9 and HoxB13, which are transcribed in the same direction. HoxB9 associates with the transcriptional cofactors BTG1 and BTG2, which enhance HoxB9 ranscription. Alterations in HoxB9 expression, as with other Hox family member, has been implicated in leukemia.Synonyms: Homeobox protein Hox-B9, Hox-2.5, Hox-2E

    分子量

    approx. 28 kDa

    基因ID

    3219

    NCBI登录号

    NP_076922

    UniProt

    P17482
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