IRF2 抗体
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北京 101111
Quick Overview for IRF2 抗体 (ABIN272167)
抗原
See all IRF2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of IRF-2 protein. (region surrounding Lys129)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Interferon Regulatory Factor 2 (IRF2) (AA 1-349) antibody
IRF2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 2 (IRF2) (AA 216-315) antibodyIRF2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-Interferon Regulatory Factor 2 (IRF2) (AA 216-315) antibodyIRF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D6 unconjugated
anti-Interferon Regulatory Factor 2 (IRF2) (AA 120-349) antibodyIRF2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 2 (IRF2) antibodyIRF2 适用: 人, 小鼠, 大鼠 WB, IF (cc) 宿主: 兔 Monoclonal 5F2 unconjugated
anti-Interferon Regulatory Factor 2 (IRF2) (AA 81-180) antibodyIRF2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 2 (IRF2) (AA 1-349) antibodyIRF2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon Regulatory Factor 2 (IRF2) (C-Term) antibodyVerified IRF2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Regulatory Factor 2 (IRF2) antibodyIRF2 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Interferon Regulatory Factor 2 (IRF2) (AA 150-200) antibodyIRF2 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IRF2 (Interferon Regulatory Factor 2 (IRF2))
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别名
- IRF2
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背景
- Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3gamma p48 (the 48 kDa component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP).Synonyms: IRF-2, Interferon regulatory factor 2
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分子量
- approx. 47 kDa
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基因ID
- 3660
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NCBI登录号
- NP_002190
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UniProt
- P14316
抗原
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