TPT1 抗体
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北京 101111
Quick Overview for TPT1 抗体 (ABIN272165)
抗原
See all TPT1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of HRF protein. (region surrounding Lys100)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 35-138) antibody
TPT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 35-138) antibodyTPT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 35-138) antibodyTPT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (Internal Region) antibodyTPT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) antibodyTPT1 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Monoclonal 10A9 unconjugated Recombinant Antibody
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) antibodyTPT1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 85-113) antibodyTPT1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19910 unconjugated
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 85-172) antibodyTPT1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) (AA 1-172) antibodyTPT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein, Translationally-Controlled 1 (TPT1) antibodyTPT1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))
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别名
- TPT1 / TCTP
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背景
- Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family and is detected as a protein of 21 kDa in mice and 23 kDa in human. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down Syndrome.Synonyms: Fortilin, HRF, Histamine-releasing factor, Translationally-controlled tumor protein
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分子量
- approx. 24 kDa
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基因ID
- 7178
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NCBI登录号
- NP_003286
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UniProt
- P13693
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途径
- Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling
抗原
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