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GALE 抗体

The 小鼠 单克隆 anti-GALE antibody is suitable to detect GALE in samples from 人, 大鼠, 犬 和 猴. It has been validated for WB 和 IHC.
产品编号 ABIN2721595
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GALE 抗体 (ABIN2721595)

抗原

See all GALE 抗体
GALE (UDP-Galactose-4-Epimerase (GALE))

适用

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人, 大鼠, 犬, 猴

宿主

  • 48
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小鼠

克隆类型

  • 50
  • 4
单克隆

标记

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This GALE antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

1C4
  • 产品特性

    Homo sapiens UDP-galactose-4-epimerase (GALE), transcript variant 1

    纯化方法

    Purified from mouse ascites fluids by affinity chromatography

    免疫原

    Full length human recombinant protein of human GALE (NP_000394) produced in HEK293T cell.

    亚型

    IgG1
  • 应用备注

    WB 1:500~2000, IHC 1:150,

    说明

    The concentration of the product may vary between diferrent lots.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5-1.0 mg/mL

    缓冲液

    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    GALE (UDP-Galactose-4-Epimerase (GALE))

    别名

    GALE

    背景

    This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.

    分子量

    38.1 kDa

    基因ID

    2582

    NCBI登录号

    NM_000403

    HGNC

    2582

    途径

    Response to Water Deprivation, Cellular Glucan Metabolic Process
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