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MED26 抗体

This 兔 多克隆 antibody specifically detects MED26 in WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN272149
发货至: 中国
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Quick Overview for MED26 抗体 (ABIN272149)

抗原

See all MED26 抗体
MED26 (Mediator Complex Subunit 26 (MED26))

适用

  • 45
  • 16
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 41
  • 4

克隆类型

  • 42
  • 3
多克隆

标记

  • 30
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MED26 antibody is un-conjugated

应用范围

  • 29
  • 22
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    MED26 (Mediator Complex Subunit 26 (MED26))

    别名

    CRSP70

    背景

    In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase. These complexes include CRSP (for cofactor required for Sp1 activation), which is required, in conjunction with TAFIIs, for transcriptional activation by Sp1. CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits. Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS. CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits also associate with larger multimeric coactivaor complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription.

    分子量

    approx. 65 kDa

    途径

    Regulation of Lipid Metabolism by PPARalpha
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