TNFSF13 抗体
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北京 101111
Quick Overview for TNFSF13 抗体 (ABIN272145)
抗原
See all TNFSF13 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of APRIL protein. (region surrounding Ser183)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (AA 105-250) antibody
TNFSF13 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2C2C11 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (AA 1-247) antibodyTNFSF13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal G3 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (AA 105-247) antibodyTNFSF13 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (AA 1-17) antibodyTNFSF13 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (Internal Region) antibodyTNFSF13 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (AA 151-200) antibodyTNFSF13 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (AA 105-250) antibodyTNFSF13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (Center) antibodyTNFSF13 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) antibodyTNFSF13 适用: 人 WB, IP, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal Aprily-8 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (AA 1-247) antibodyTNFSF13 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH ~7.2, 15 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))
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别名
- CD256 / APRIL
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背景
- A proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. APRIL is expressed in high levels in transformed cell lines and in human colon, thyroid, and lymphoid tumor tissues. APRIL is critically involved in the regulation of infections, inflammation, autoimmune diseases, and tissue homeostasis. APRIL is implicated in the regulation of tumor cell growth. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.Synonyms: A proliferation-inducing ligand, TALL-2, TALL2, TNF- and APOL-related leukocyte expressed ligand 2, TNF-related death ligand 1, TNFSF13, TRDL-1, Tumor necrosis factor ligand superfamily member 13, ZTNF2
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分子量
- approx. 22 to 32 kDa
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基因ID
- 8741
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NCBI登录号
- NP_003799
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UniProt
- O75888
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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