HBP1 抗体
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Quick Overview for HBP1 抗体 (ABIN272139)
抗原
See all HBP1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of HBP1 protein. (region surrounding Leu468)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-HMG Box-Containing Protein 1 (HBP1) (AA 421-514) antibody
HBP1 适用: 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (C-Term) antibodyHBP1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (AA 1-514) antibodyHBP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (C-Term) antibodyHBP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (C-Term) antibodyHBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 豚鼠, 小鸡, 马, 兔, 非洲爪蟾, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (AA 396-445) antibodyHBP1 适用: 人, 大鼠, 犬, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (Middle Region) antibodyHBP1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (Middle Region) antibodyHBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (N-Term) antibodyHBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (pSer402) antibodyHBP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- HBP1 (HMG Box-Containing Protein 1 (HBP1))
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别名
- HBP1
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背景
- The HMG-box protein-1 (HBP1) is a member of the HMG family of transcription factors, which are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, that mediates DNA binding. HBP1 binds to the tumor suppressor proteins Rb and p130 and initiates cell cycle arrest. Terminal cell differentiation requires this initial cell cycle arrest followed by the coordinated expression of genes defined as tissue-specifc markers. Along with initiating the commitment to cell differentiation, the continued activity of HBP1 abrogates the expression of tissue-specific genes by associating with the MyoD proteins. In muscle cell differentiation, the MyoD family of transcription factors, which include Myf5, MyoD and myogenein, induce the expression of these cell-type specific proteins and contribute to the development of cell phenotypes. The progression of terminal differentiation is, therefore, dependent on both a decrease in HBP1 activity and the corresponding activation of MyoD-induced gene transcription.Synonyms: HMG box transcription factor 1, HMG box-containing protein 1, High mobility group box transcription factor 1
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分子量
- approx. 50 kDa
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基因ID
- 26959
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NCBI登录号
- NP_036389
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UniProt
- O60381
抗原
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