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T-Box 1 抗体

The 兔 多克隆 anti-T-Box 1 antibody (ABIN272136) specifically detects T-Box 1 in WB, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN272136
发货至: 中国
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Quick Overview for T-Box 1 抗体 (ABIN272136)

抗原

See all T-Box 1 (TBX1) 抗体
T-Box 1 (TBX1)

适用

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宿主

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克隆类型

  • 58
  • 14
多克隆

标记

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  • 1
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This T-Box 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of TBX1 protein. (region surrounding Lys347)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    T-Box 1 (TBX1)

    别名

    TBX1

    背景

    The T-box (TBX) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The TBX gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. TBX genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in TBX genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of TBX products has come mainly from the prototypical T/Brachyury, which is a transcription activator. The TBX genes constitute a family of transcriptional regulatory genes that are implicated in a variety of developmental processes ranging from the formation of germ layers to the organizational patterning of the central nervous system.Synonyms: T-box protein 1, T-box transcription factor TBX1, Testis-specific T-box protein

    分子量

    approx. 43 kDa

    基因ID

    6899

    NCBI登录号

    NP_005983

    UniProt

    O43435

    途径

    Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
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